Robaxin vs Flexeril: Differences, similarities, and which is better for you

The immediate effects of cyclobenzaprine typically last from 4 to 6 hours after oral consumption of the medication. However, cyclobenzaprine, even the immediate-release formulation, has a half-life of 18 hours. Extended-release forms of the drug remain in your system for up to 37 hours. This means that people abusing a cyclobenzaprine high can be affected for a prolonged period.

• Robaxin needs to be taken three to four times a day to provide relief from muscle pain and muscle spasms.
• However, cyclobenzaprine is one of the most studied muscle relaxers with strong evidence for its effectiveness.
• Spasticity is defined as a velocity-dependent increase in muscle tone that manifests with resistance to movement and involuntary muscle spasms and contractions.
• There are no adequate studies to show that Robaxin or Flexeril are safe or harmful during pregnancy.
• Keep in mind that regular cyclobenzaprine tablets may require dosing of up to 3 times a day.

Flexeril is also known to cause other side effects such as constipation and nausea. Cyclobenzaprine relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system disease. Evidence suggests that the net effect of cyclobenzaprine is a reduction of tonic somatic motor activity, influencing both gamma (γ) and alpha (α) motor systems.

Cyclobenzaprine Dosage and Administration

Also, methocarbamol and cyclobenzaprine are not recommended in pregnant women, elderly adults, and young children. Zanaflex may cause liver injury in some people, especially those who have a history of liver impairment. Flexeril should also be used with caution in individuals with liver problems.

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Both cyclobenzaprine and tizanidine were found to be effective for musculoskeletal conditions such as acute neck or back pain. You may be skeptical about the possibility of a cyclobenzaprine high. One report found that some people were engaging in cyclobenzaprine recreational use, in combination with illicit drugs, in an attempt to experience psychoactive effects.

Alcohol can compound muscle-relaxant side effects such as drowsiness, dizziness, or loss of coordination. Muscle relaxants should be avoided or monitored before operating machinery or driving a motor vehicle. Muscle relaxants like Robaxin or Flexeril can cause increased dizziness or drowsiness and impair cognitive performance. Even if you have insurance, the prices of Robaxin, Fexmid, Amrix, and other muscle relaxants may be cheaper through the BuzzRx discount program.

If you have muscle spasms or muscle pain and plan to take skeletal muscle relaxants, please work with your healthcare provider to find the one that works best for you. Keep in mind that along with medications for short-term alleviation of pain and discomfort, rest and physical therapy can help with long-term pain relief and function. Both Zanaflex and Flexeril are drugs used for muscle scivation flexeril spasms and pain relief from musculoskeletal conditions. Zanaflex is commonly prescribed to treat spasticity from multiple sclerosis, cerebral palsy, and spinal cord injury. Flexeril is often prescribed to relieve muscle pain and spasms caused by back and neck strains. Muscle relaxants are some of the most commonly prescribed medications to treat back pain and other strains or sprains.

Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepressants. Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system (CNS) as a depressant that reduces muscle hyperactivity. Robaxin contains methocarbamol and is usually dosed multiple times per day. Flexeril contains cyclobenzaprine and is available in an extended-release form that can be taken once per day. Drug comparisons between cyclobenzaprine and methocarbamol in terms of side effects do not reveal many differences. Both medications can cause adverse effects such as dizziness, drowsiness, headache, nausea, and fatigue.

International Patients

Some people may prefer extended-release generic Flexeril for its once-daily dosing. But, Flexeril may also cause more adverse effects like drowsiness and dry mouth. Discuss these treatment options with a doctor to find the best medication for you. Both Robaxin and Flexeril work in similar ways through acting on the central nervous system (CNS).

Abuse and dependence may occur with long-term use and lead to addictive habits. Professional treatment programs at Sunlight Recovery are designed to help you or a loved one safely detox from cyclobenzaprine and take back control of your life. We offer outpatient therapy, residential treatment programs and group therapy options to ensure our services meet you exactly where you are.

Cyclobenzaprine acts a muscle relaxant and can be used to treat musculoskeletal conditions that result in muscle spasms. It’s also prescribed when patients have strained muscles through physical activity and need immediate relief. It’s sold under the brand names Flexeril and Amrix in the United States. The drug acts on the central nervous system — specifically, on the brain, rather than the spinal cord.

Cyclobenzaprine with ibuprofen versus ibuprofen alone in acute myofascial strain: A randomized, double-blind clinical trial

If one has overdosed on the combination, immediate medical detox is required. The medicine treats the condition by providing intermittent relief to the pain caused due to the spasms. It blocks the pathway of neurotransmitters that are responsible for the sensation of pain. It relaxes only the muscles and not the actual causative nerves behind the pain. For best results, doctors recommend combining the use of Flexeril with rest and physical therapy.

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Our Flexeril (cyclobenzaprine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.

It’s Often a Fruitless Combination

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Using this medicine blue flexeril 10 mg with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

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Because of the possibility of higher blood levels in the elderly as compared to younger adults, use of cyclobenzaprine extended-release capsules is not recommended in the elderly. Appropriate studies have not been performed on the relationship of age to the effects of cyclobenzaprine extended-release capsules in the pediatric population. Consuming any medication together could be harmful for individual. Although this can lead to serious side effects like drowsiness and nausea.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. The incidence of drowsiness, the most frequent adverse reaction, was similar with both drugs.

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The immediate-release tablets last for about four to six hours, while the extended-release tablets last around 24 hours. Cyclobenzaprine is usually taken once daily for only 2 or 3 weeks. Avoid driving or hazardous activity until you know how this medicine will affect you. Older adults may be more sensitive to the effects of this medicine.

• These feelings may potentially be a cause for misuse of Flexeril and lead to addictive effects.
• Use of FLEXERIL for periods longer than two or three weeks is not recommended.
• Novocaine is a medication that belongs to the drug class local anesthetics.
• Eight double-blind controlled clinical studies were performed in 642 patients comparing FLEXERIL 10 mg, diazepam, and placebo.
• Flexeril is a medication belonging to a class of skeletal muscle relaxants used to treat muscle spasms.

Cyclobenzaprine is a drug prescribed to treat pain and discomfort. This page will go over its side effects, drug interactions, and treatment for misuse. The overall incidence of adverse reactions among patients in the surveillance program was less than the incidence in the controlled clinical studies. Flexeril and ibuprofen can provide a more comprehensive approach to managing back pain when used together.

Combining these two can cause extreme dizziness or drowsiness, low blood pressure, or liver damage. Muscle relaxants affect your nervous system, so taking another drug that affects your nervous system such as opioids or psychotropics should be avoided, according to Healthline. You also don’t want to take St. John’s wort or sleeping medications while on muscle relaxants.

Find Another Drug

The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly). The elderly may also be more at risk for CNS adverse events such as hallucinations and confusion, cardiac events resulting in falls or other sequelae, drug-drug and drug-disease interactions. For these reasons, in the elderly, cyclobenzaprine should be used only if clearly needed.

Then you freak out, wondering if taking both muscle relaxers and ibuprofen might cause a negative interaction. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Additionally, prescription muscle relaxers are not entirely safe and can cause addiction.

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